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1.
Someone who resembles a heavier Matt Damon and hits on women in Public.
The only way to defend against a Fat Damon is to address everyone in the vicinity, and in the most retarded voice possible proclaim, "Faaaaat Daaaamon".
Guy1: "Hey buddy, you better keep an eye on your girl. Looks like she's getting Fat Damoned at the bar."

Guy2: Approaches the bar gaining the attention of all around and proclaims in a retarded voice, "Faaaaaat Daaaaamon."
von vector 2518 SBS 10. Januar 2011
 
2.
an insult towards fat people. the humor of the term gets its punch because it rhymes with actor Matt Damon.
Doug: Carrie! You ARE abusive towards me! You make fun of my weight all the time!

Carrie: I do not!

Doug: Oh yeah? What about the time you called me Fat Damon? That was five minutes ago!!
von C. Norton 24. Februar 2009