Top Definition
The urge to hurdle over anything while yelling "McGuffie!"
Me: Hey, I think my roommate and her boyfriend have McGuffie Fever.
Friend 1: Why do you say that?
Me: (*points to roommate*)
Roommate: *runs and hurdles over a bench* while yelling, "McGuffie!"
von OGMcGuffieFever 8. November 2009
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