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2.
To have some very burdensome nuisance you have to put up with--in a sense wider than just a drug or other addiction.
"That huge credit card payment is a real monkey on his back." "Trying to sell that white elephant must be a monkey on your back."
von Guthlac A 9. Februar 2010
 
1.
To have an addicction, especially a drug addiction.
Man, he's got a monkey on him back! He's so wasted!
von bluestorm100 12. März 2005
 
3.
To have a deep, uncontrollable desire to something such as Gamble, Smoke, or Drink.
Man he has that Drinking monkey on his back, it is 9:30 in the morrning and he's already drunk.
von Stan, Ricky, Cody, and Alex 3. April 2003
 
4.
Addiction, mostly heroin/morphine addiction.
Hey dad, you been smacking da H again, quit it bitch, you have a monkey on your back

But the morphine eased the pain,
And the grass grew round his brain,
And gave him all the confidence he lacked,
With a Purple Heart and a monkey on his back.

There's a hole in daddy's arm where all the money goes,

-John Prine - 'Sam Stone' a song about a vietnam vet returning to the US with a monkey on his back.
von GG Allin11 1. September 2013
 
5.
Severe relentless back pain one gets during opiate withdrawal.
hardest part of detox will be the monkey on your back
von XsubZ 16. April 2010