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1.
OPE
1: A reaction for something small but silly happening.

2: Said after a witty remark.
Ex.1: General. OPE!

Ex.2:

P1: Fatty says what?
P2: What?
P1: OPE.
von Niko Jims 9. Januar 2010
 
2.
Opium or any opiate/opioid (oxycodone, codeine, hydrocodone, heroin, morphine, fentanyl.. whatever)
"I could really go for some opes right now"

"OOOOPPPPEEEEESSSS" (to be said in a raspy ope-voice while under the influence)
von abeeler 21. Februar 2008
 
3.
(noun) -An interjection of surprise after an unexpected event occured. It can be for either bad or good connotation depending on the situation.
You and a friend are fighting over an ice cream cone and it slips out of your hands and lands on your dogs head, so you and your friend look at each other and say, "Ope!"
von YaMommasDaddy 18. Januar 2012
 
4.
or 'opez', used as replacement for 'oops' as in when one makez a mistake.

bobz: nice beat mane, itz hot.

jimmz: i didn't make it mane.

bobz: opes, my bad.
von John3:30 2. März 2009
 
5.
ope
Another name for the drug opium
You down with ope?

You know it!
von davethelurker 20. September 2006
 
6.
ope
no longer do you have to choose between the words ape and oaf, ope is a word that encapsulates both!
Jonny wilds is an Ope
I behaved like an Ope last night
von David O'Connor 7. Oktober 2007
 
7.
ope
A instinctive reaction when you see a chick and you immediately know you would.

Often followed by staring at said chick with hand in a fist shape covering ones mouth.
:See a fine chick walking:
OPE! She go!
von Amoneyies 5. August 2010