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1.
The systematic wasting away of brain matter
Guy 1: What is with him recently?

Guy 2: He's been doing a lot of drugs, caught crabs and has Poseidon's Disease.

Guy 1: That explains why he's getting stupider
von MamboNZ 7. April 2009
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Words related to Poseidon's Disease:

dimentia disease dullard posedion stupid wasting