verb. To screw up something or everything by your inexplicable actions as every Mark Ruffalo character manages to do.
Wow, he really ruffaloed his marriage by sleeping with his secretary.
I don't want to pull a ruffalo here, so I'm just going to go home to sleep.
I'm trying not to ruffalo this relationship with my neuroses.
von Terry Prescott 17. Juli 2009

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