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1.
S5
The abbreviation for a Stage 5 Clinger.

Someone who has passed the first 4 stages of stalking and has graduated to a complete level 5.
Boy: Yo, that girl is always stalking me!
Girl: Mhm.. she's a real S5!
von THipp 4. April 2011
 
2.
S5
Area of sensation around the anus, supplied by the 5th sacral nerve, or S5. Also can be used in reference to anal sex.
My girl finally gave up the S5 last night, and it was fuckin' awesome!

I let my boyfriend have my S5, and I came so hard when he did.
von lola time 6. August 2007
 
3.
s5
It means "back" in slovak language. Its original spelling in slovak language is "spat".
O chvilu som spat. {O chvilu som s5} - "I`ll be right back".
von masi&trupik 21. Mai 2008