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1.
Slang for syphilis, a venereal disease.
He got syfy on the downlow.
von Science Boy 16. März 2009
 
2.
1. Originating in Polish, meaning zits, cum or filth in the plural and syphilis in its singular form ("syf").

2. Slang term for syphilis, often used in a mocking or even affectionate fashion.

3. Name of a TV network that shows imagination-based programming to go with their illusionary ratings. Failing after a re-branding press release insulted its core audience.
1. Co to za syfy? (Eng.: What is this crap?)

2. Aww, man, you better wear some protection or you'll get the syfy.

3. There's never anything good on the Syfy.
von Cricket_B 18. März 2009
 
3.
A modern butchering of the previously named "Sci-Fi Channel", which is about all things sci-fi.
"Hey remember when Syfy was called Sci-Fi Channel?"
"Those were the days.."
von Noel Ratsu 8. August 2009
 
4.
An abbreviation or slang term for syphilis.
"Yo, dude! Did you hear that Jo-Jo caught syfy from that crack ho?"
von ZeroCorpse 16. März 2009
 
5.
abbreviation of "screw you, fuck you". Used in texting.
You think my sister's a ho? syfy!
von DarcDweller 18. März 2009
 
6.
New phonetic spelling for the Sci Fi channel. This is so people texting about their favorite programs on the channel will not have to unnecessarily overtax their brains or thumbs.
trek tonite syfy @ 8 make it so
von whathappenedtorealscifishows 16. März 2009
 
7.
Miss spelling of the channel SciFy
What's the best channel on cable? SyFy
von NESSKART Racing 1. September 2009