1. A way to shorten the phrase whats up. When your saying hello to a lass, its easy to say whayup rather than whats up.

2. A verb to express either jizzing, shitting, or anything that involves domination.
1. Bobby: Oh hey Jennifer, whayup!

Jennifer: Not alot Bobby, how are you.

2.

Guy 1: Bro I just whayuped all over Stephanie's face after she gave me head.

Guy 2: Dude, that's whayup.
von yanni33 29. Januar 2010

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