Top Definition
able to function well with difficult mental or physical tasks while very sleepy.

Ambien (sleeping medication)+dexterous(skillful)
Wow, you are ambiendextrous to be able to parallel park that school bus on three hours of sleep without hitting anything!
#dexterous #ambidextrous #clumsy #agile #ambiendexterous
von whimsical_icicle 26. Oktober 2010
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