Top Definition
A contagious, often fatal epidemic disease which lolwtfpwnd a third of the world's population. The bubonic plague is caused by the bacterium Yersinia pestis, transmitted from person to person or by the bite of fleas from an infected host, especially a rat, and characterized by chills, fever, vomiting, bloody semen, diarrhea, and the formation of buboes.
Me: I have the bubonic plague. My lymph nodes R hurt.
Onlooker: You are lolwtfpwnd.
von sux0r 30. April 2006

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