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1.
A term used in the D/s community for a submissive who's responsable for taking care of the home, cleaning up after play paries, and tending to any needs of the Dom.

A house mouse is usualy Not collared by the Dom they work under.

The payments and punishments of a good or badly done job are usualy defined by the Dom.
Master P has a cute lil house mouse, she'll get on her knees and scrub the floor - then polish his knob.
von QueerFemmeGirl 4. Januar 2007
 
2.
Usualy used in motorcycling circles, to describe a female of questionable virtue, who tends to drift from house to house; bed to bed; person to person. Often repeating themselves throughout the course of a year.

Or

A motorcycle groupy.
"So... your seeing so and so... eh"

"Yeah... I realy like her man."

"Well don't get to attached... she's a bit of a House Mouse... and Kevin just got a new Duc
von schimschone 12. März 2005
 
3.
A snitch.
"Better move that fucking contraband. First Sergeant's house mouse just saw you shove it underneath there."
von Doc Soul 6. April 2009
 
4.
Boobs, tits, breasts.
Damn, Molly has some nice house mouses!
von Jason B 13. März 2003