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1.
Stands for Hell Yeah Fucking Right. It's what is said when you are so sure of something that you don't even have to hesitate think about it.
Person 1: Are you sure these people are your real friends? Will they be their for you no matter what?

Person 2: HYFR.
von Prince1020 7. August 2012
 
2.
It means, Hell Yeah, Fucking Right. It comes from Drake's kit song, HYFR. Most commonly used on Facebook and Twitter, this abbreviation has just recently become known. Mostly used by wanna-be gansters and thugs.
Ayy brah, d'you see that hottie at the beach yesterday?!

"HYFR bro!"
von WhoCares17 30. November 2011
 
3.
Stands for "Hell Ya Fucking right" One of Drakes song "HYFR" Take Care'
Girl: Do you love this shit? Are you high right now? Do you ever get nervous? Are you single? I heard you fucked your girl, is it true? You getting money? You think them niggas you with is with you?

Guy: "HYFR!!!!!"
von DrakeIsYourDADDi 21. November 2011
 
4.
Hell Yeah Fuckin' Right, a song of Drake's album 'Take Care'
raj: dude, drake is raw as hell

bob: hyfr
von MrMeditation1 6. November 2011