1.A program proposed by Apple, which incorporated sex into the Mac OSX desktop, which was initially accepted and then rejected, after CEO's thought that it might be contrary to Apple's public image.

2. Internet sex via two Macintosh Computers.

3. A computer with a ridiculous amount of porn on it.
Man, I was really looking forward to iSex.

Boy: Hey wanna iSex?
Girl: Wait 'til my parents leave.

Friend: Damn! Your computer is a freaking iSex
von Johnathan Mc Nads 11. April 2006
Listening to music while getting you're thing on!
Let's get it on with the iSex going!
von Quentin_B 6. November 2006
Sex via digital media e.g skype, facetime and other webcam tool software
My girlfriend and I had I-Sex by pleasing ourselves while communicating over the internet
von Yuri Balie 1. April 2013

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