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2.
Commonly used to say someone is moving, but not in this case. In this case, it can mean, crazy, weird, or annoying.
Madison and Neal are on the run.
von katy. taylor. britney. <3 7. April 2010
 
1.
1. moving from place to place

2. running from the police
I almost never eat breakfast while on the run.
von Light Joker 20. Januar 2007