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1.
The four letters on the keyboard above asdf.
von mista conspiracy 27. Mai 2005
 
2.
A way to say queer when it has been used up, a way to put in
variety in your insults that usually mean Gay, even if the victim is not.
"Ah, Qwer!"
"You Qwer!"
von Artifishalfish 31. Juli 2006
 
3.
Left hand placement for special commands/spells in an online game that is from a third person-ish view, where you control a hero/champion in a person to person battle within a contained map that has an element of base/tower defense and attack with NPC (non-player character) minions. All this happens in a real time, multi-player map/environment and is considered an adventure, real-time strategy & role playing game like LOL (League Of Legends) or DOTA (Defender Of The Ancients).
As a summoner, I'll use the mouse to control my champions movement and target and then QWER POWER...*press Q* mega damage powers! *press W* Suck it monkeys! *press E* Boo-ya! *press R* How do you like them apples?! *frustrated keyboard smash* Why did I die?
von Zeomox 20. August 2013
 
4.
thought up in about the year 2002 by retarded "preps" who can't talk. most of them have speech impetiments. means "queer" or "gay" or "fag", anything along that line. typically used after someone's name. it is used quite often so i wonder if there isn't a sign of homosexual tendecies.
"Pensak, QWER!" or "Jordan Pensak, QWER!" in order to complete it you have to have a lisp on the S's
von prepdawgslikeitinthebutt 8. Juli 2004